INCI: Lactobacillus Ferment & Lactobacillus & Cocos Nucifera (Coconut) Fruit Extract

You can #preserve #naturally and #effectively, while adding #moisturizing and #conditioning power to your #skincare products!

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100mL in an amber glass bottle
250mL in an amber or blue glass bottle
500mL 10% volume discount BYOB - Bring or Buy Your Own Bottle
1000mL 20% volume discount BYOB - Bring or Buy Your Own Bottle
CLEARANCE WHILE SUPPLIES LAST 30% OFF FOR 1 LITRE+.
The price you see is already 30% off the base price.

Bring the right-sized bottle for me to fill on pick up or buy a bottle here.
You can bring your own bottle on pick up or buy a bottle here

#Natural #antimicrobial products are similar to synthetic #preservative systems in that they are effective against #bacteria, however, most natural antimicrobial products lack broad-spectrum effectiveness against bacteria AND fungi, specifically yeast and mold. Leucidal® SF Complete uses a combination of peptide technology to deliver moisturizing and conditioning benefits as well as provide a broad-spectrum activity to protect against bacteria, yeast, and mold in one product.

Leucidal® SF Complete combines the antibacterial power of Leucidal® Liquid SF and the antifungal power of AMTicide® Coconut to deliver an effective, salicylate-free one-step solution! This highly marketable product can provide moisturizing and conditioning benefits for hair and skin care applications. Leucidal® SF Complete is effective at preventing the growth of bacteria and fungi, including yeast and mould, making it the perfect addition to any formulation.

Leucidal® SF Complete is a mixture of antimicrobial peptide technology. One type of antimicrobial peptide is originally derived from the lactic acid bacteria, Lactobacillus. Like many members of the lactic acid bacteria family, Lactobacillus is capable of restricting the growth of other microorganisms by acidifying its environment. However, Lactobacillus also produces novel antimicrobial peptides known as bacteriocins that are capable of providing effective protection against bacteria. Lysozyme is added to the ferment filtrate during the manufacturing process to facilitate controlled cell lysis and ensure the release of the antimicrobial peptides for maximized activity. Using modern fermentation and bioprocessing technology, Active Micro Technologies has commercialized this antimicrobial peptide to produce Leucidal® SF Complete.

The other type of antimicrobial peptide is created from fermenting Cocos nucifera (Coconut) with Lactobacillus. Coconut oil has been traditionally used to treat skin disorders, yeast infections, ringworm, and even athlete’s foot. About 50% of the total fatty acid content of coconut oil is medium chain triglycerides (MCTs) that exhibit natural antifungal activity. MCTs, such as lauric acid, work by disrupting the cellular structures of fungus and destroying them before they can wreak havoc. During the fermentation process, lipopeptides are catabolized by the MCTs present in coconut flesh. Active Micro Technologies has harnessed natural phyto compounds and lipopeptides from coconut to produce a novel antifungal material.

Natural antimicrobial products are similar to synthetic preservative systems in that they are effective against bacteria, however, most natural antimicrobial products lack broad-spectrum effectiveness against bacteria and fungi, specifically yeast and mold. Leucidal® SF Complete uses a combination of peptide technology to deliver moisturizing and conditioning benefits as well as provide a broad-spectrum activity to protect against bacteria, yeast, and mold in one product.

A skin moisturization study was performed using an untreated control, a generic cream base, and an experiment with the same cream base containing 2.0% Leucidal® SF Complete.

Comparative moisturization results from this study are shown in Figure 2. As demonstrated by the results of this study, the addition of 2.0% Leucidal® SF Complete improved moisture levels by 42.42% after 24 hours and by 63.00% after four weeks when compared to the untreated control. When compared to the base cream Leucidal® SF Complete improved moisturization by 14.38% after 24 hours and by 25.00% after four weeks. Based on these results, adding this innovative product provides the formulator with the opportunity to capitalize on both the natural antimicrobial properties of Leucidal® SF Complete, as well as its ability to provide potent moisturizing benefits to the cosmetic formulation. These properties make it ideal for applications addressing numerous skin and scalp conditions.

One of the first steps in the development of Leucidal® SF Complete was to determine the product’s potential ability to inhibit the growth of a variety of bacteria and fungi. Using standard serial dilution protocols in growth media, the Minimum Inhibitory Concentrations (MICs) for Leucidal® SF Complete were determined for a variety of bacterial and fungal organisms.

The positive MIC screening results warranted further testing to confirm its ability to provide product preservation. A Double Challenge Test was completed using 2.0% Leucidal® SF Complete in a generic cream base formulation. Samples were inoculated with E. coli, P. aeruginosa, S. aureus, C. albicans, and A. brasiliensis. During the first 28-day incubation period, samples were periodically collected and tested for the presence of these microorganisms. Following this initial 28 days of incubation, the cream samples were then re-inoculated with the microbial cultures and sampled over an additional 28-day period. Figure 4 shows the positive preservation results for Leucidal® SF Complete.

As with all biological materials, attention must be paid to the conditions under which Leucidal® SF Complete is used. Based on bench-scale evaluations, as well as actual product applications, Leucidal® SF Complete is effective over a wide range of topical cosmetic and personal care product manufacturing conditions. The product is heat stable up to 70°C and active under both acidic (pH 3) and basic (pH 8) conditions.

Suggested Use Levels: 2-4%
Appearance: Clear to Hazy, Colorless to Light Yellow Liquid
Solubility: Water Soluble
pH: 7.0-10.0

Storage: Protected from direct light and humidity at a temperature of 50°-77°F (10°-25°C)

Shelf life: 12 months, properly stored, in a sealed container. This product should be added to a formulation at the recommended usage rate

IMPORTANT: All of our products are for external use only.

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